Profiling prefrontal cortex protein expression in rats exhibiting an incubation of copyright craving following short-access self-administration procedures

IntroductionIncubation of drug-craving refers to a time-dependent increase in drug cue-elicited craving that occurs during protracted withdrawal.Historically, rat models of incubated copyright craving employed extended-access (typically 6 h/day) intravenous drug self-administration (IV-SA) procedures, although incubated copyright craving is reporte

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Using the Many-Facet Rasch Model to analyse and evaluate the quality of objective structured clinical examination: a non-experimental cross-sectional design

Objectives Sources of bias, such as the examiners, domains and stations, can influence the student marks in objective structured clinical examination (OSCE).This study describes the extent to which the facets modelled in an OSCE can contribute to scoring variance and how they fit into a Many-Facet Rasch Model (MFRM) of OSCE performance.A further ob

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Expression of genes associated with immunity in the endometrium of cattle with disparate postpartum uterine disease and fertility

Abstract Background Contamination of the uterine lumen with bacteria is ubiquitous in cattle after parturition.Some animals develop endometritis and have reduced fertility but others have no uterine disease and readily conceive.The present study tested the hypothesis that postpartum cattle that develop persistent endometritis and infertility are un

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